Nestled on the banks of the picture-perfect Ohio River, Louisville is arguably one of the most underrated cities in the US. From going bar-hopping along the city’s famous Whiskey Row to attending the annual Kentucky Derby, there are just so many incredible things to do in Kentucky‘s largest city!
First-time visitors will definitely want to celebrate the city’s deeply engrained sports culture at the Muhammad Ali Center, the Kentucky Derby Museum, and the Louisville Slugger Museum and Factory. If you’re in town during baseball season, be sure to catch a Louisville Bats game at Louisville Slugger Field!
From local distilleries to farm-to-table eateries, Louisville is a mecca for foodies. No trip to the city is complete without sampling its famous fried chicken, Derby Pie, and Hot Brown sandwiches. And don’t forget to top it all off with a tall pour of fine Kentucky bourbon!
From perusing the city’s world-class museums to taking a sunset cruise on The Belle of Louisville steamboat to embarking on Kentucky’s boozy Bourbon Trail, Louisville has something for everyone. There’s a reason why more and more visitors are flocking to this incredible city year after year!
It’s no surprise that Louisville boasts all sorts of luxurious historic hotels, bourbon-themed boutique hotels, and industrial-chic warehouse hotels. So many, in fact, that you might have a hard time choosing the perfect one. So we’ve created a list of the 12 best hotels in Louisville to help you plan your perfect getaway!
Don’t forget to check out our web story: The 12 Best Boutique Hotels In Louisville, Kentucky
Disclaimer: This post may contain affiliate links. If you make a purchase or booking through one of our links we may earn a small commission (don’t worry, it’s at no extra cost to you).
Where to Stay in Louisville
It’s no surprise that the best hotels in Louisville are located in the bustling downtown area. If this is your first visit to the city, this is the best place to base yourself. You’ll be a stone’s throw from all of Louisville’s iconic attractions, including the Louisville Slugger Museum and Factory, the Muhammad Ali Center, and Waterfront Park.
Old Louisville is also a great area to stay for first-timers. Downtown is a quick 10-minute drive away. Plus, it’s impossible not to be charmed by the neighborhood’s tree-lined streets, historic buildings, and quaint eateries!
Some of the coolest boutique hotels in Louisville can be found in the up-and-coming Butchertown neighborhood. This area has undergone a massive revitalization in recent years, and many of its old meat production plants have been converted into trendy hotels, eateries, and shops.
Located right next to downtown, NuLu is arguably the coolest place to stay in Louisville. The neighborhood is brimming with art galleries, distilleries, and some of the best restaurants in town! Plus, you’ll be able to walk to some of the city’s most iconic attractions.
The 12 Best Hotels in Louisville, Kentucky
1. Hotel Distil
As the name implies, Hotel Distil is set among a bunch of former liquor warehouses on Louisville’s historic Whiskey Row. One of the most unique things about this place is that every detail is rooted in the city’s bourbon culture and prohibition-era history.
At check-in, you’ll be handed a medical prescription card, just like during prohibition! You can use it at the hotel’s evening toast to end prohibition. This pet-friendly hotel will even provide your pups with an adorable handmade bourbon barrel dog bed, a custom PupJoy Box, and a Hotel Distil brand chew toy!
One of the coolest things about this hotel is that it’s home to Bitters End, the only open-air rooftop bar on Whiskey Row. For incredible steak dinners, Repeal uses a hand-stoked wood-fired grill and oak-age barrels to prepare its seriously good steaks. Or, for a private dining experience, The Barrel Room is perfect for special occasions and VIP gatherings.
After all that bourbon, you’ll love crashing out in the luxurious rooms. All rooms boast plush beds with leather headboards, large flat-screens, and luxe ensuites. If you’ve got a hankering for more bourbon, you can even ask to have a carefully curated Bourbon Cart set up in your room for an extra fee!
The Grady Hotel recently opened its doors in March 2021 but it didn’t take long for this historic gem to become known as one of the best boutique hotels in Louisville! Housed in a former medicinal bourbon apothecary dating back to 1883, expect to find original architectural elements, vintage decor, and modern amenities throughout this one-of-a-kind hotel.
The 51 picture-perfect rooms are the epitome of style and luxury. You’ll love the 10- to 15-foot original reclaimed wood ceilings, floor-to-ceiling windows, comfy beds with oversized headboards, and the selection of locally-inspired art. Plus, with their marble counters, spacious walk-in showers, and designer toiletries, the bathrooms are as luxurious as it gets.
Fuel up for the day with the hotel’s artisanal continental breakfast. The Grady is located right on Main Street, so once you’re ready to explore, the Louisville Slugger Museum, the Muhammad Ali Center, and the scenic Ohio River are all just steps away.
After a long day exploring this dynamic city, head down to the rustic-chic Wild Swann bar and restaurant. It’s a prime spot to enjoy tall pours of bourbon and handcrafted cocktails while snacking on locally inspired shared plates.
If you want to stay in one of the most unique boutique hotels in Louisville, look no further than 21c Museum Hotel. Art enthusiasts will definitely want to book a stay at this hotel/art gallery! Plus, this hotel is perfectly positioned on Museum Row, so you’ll have endless galleries to explore.
Inside the hotel, you’ll be able to peruse the 9,000-square-foot gallery, which is brimming with vibrant paintings and funky installations. The art theme extends to the rooms and suites, which all boast original artwork.
All rooms are the perfect blend of historic architectural details and modern amenities. You’ll love the exposed brick walls, custom-designed furniture, and luxurious ensuites with Malin+Goetz bath amenities. It’s well worth upgrading to one of “The Balconies” rooms for their furnished rooftop terraces overlooking historic 7th Street.
The hotel is also home to Proof on Main, which is popular among locals and guests alike. The restaurant is partnered with Woodland Farm and a range of regional artisans, so expect inventive locally sourced dishes and a menu of over 120 Kentucky bourbons! If you want to cap off your day with a massage, 21c Museum Hotel also has an excellent on-site spa.
The Brown Hotel is tucked away in a 1923 building in the heart of the Theater District. Expect the perfect mix of old-world luxury and the most modern of amenities. Step inside this historic hotel’s grandiose lobby and you’ll immediately see why this iconic building is home to one of the best hotels in Louisville!
The entire building was recently given a $12 million renovation, so expect nothing but the best. The rooms have all been upgraded but still retain their historic charm, classic furnishings, and eclectic artwork. If you upgrade to one of the club-level rooms, you’ll get access to the hotel’s exclusive lounge.
For fine dining, don’t miss out on an elegant meal at English Grill. The hotel’s J. Graham’s Cafe is another must-visit for their iconic Hot Brown – basically an open-faced turkey sandwich with bacon and a Mornay sauce. And if you’re in the mood for a tipple after your meal, head down to the elegant Lobby Bar and Grill.
To glimpse some of the best views of Louisville’s skyline, pay a visit to the hotel’s incredible rooftop garden. It’s the perfect place to crack open a bottle of wine and watch the sun sink over the city!
Located directly on the Ohio River and connected to the KFC Yum! Center, this historic hotel is the epitome of luxury. You’ll be surrounded by all of Louisville’s best attractions but with so many amazing amenities, you won’t need to leave this dreamy hotel if you don’t want to!
Spend your days soaking up the river views from the outdoor pool, getting massages at the on-site spa, and keeping up with your exercise routine in the fully outfitted gym. And when it comes to food and drink, you’ll be spoiled for choice with a whopping six on-site restaurants!
If you want to have dinner or drinks with a panoramic view, head up to Swizzle on the 25th floor. For a taste of the historic Whiskey Row or the Urban Bourbon Trail, Down One Bourbon Bar and Jockey Silks both offer a unique bourbon experience. Or, to sample all of Louisville’s local favorites, make reservations at Walker’s Exchange.
After you’ve had your fill, you’ll love unwinding in the contemporary rooms. All rooms boast plush beds, comfy sitting areas, and spacious workstations. The in-room coffeemakers, soft robes, and sweeping city views are nice added features.
Moxy is the perfect pick if you’re looking for a forward-thinking boutique hotel on Whiskey Row. This place is all about having a good time. One of the many things that makes Moxy stand out from the rest is its one-of-a-kind check-in process.
Step inside the Insta-worthy lobby and head straight to the bar, which doubles as the front desk. The ultra-friendly staff will greet you with your room key and a complimentary handcrafted cocktail! You’ll be in instant vacation mode.
You’ll love all of the high-tech amenities and modern comforts of the smart rooms. Rooms boast boho-chic decor, comfy beds with leather headboards, and 55-inch HDTVs. There’s also a fold-out desk and cozy sitting area if you need to catch up on emails or want to hunker down with a good book.
You might be surrounded by some of the most popular bars in town, but Bar Moxy is a popular place to grab drinks before heading out to Whiskey Row. After a boozy night on the town, Moxy’s Zombie Taco is open till the wee hours for late-night tacos and burritos.
Aloft is yet another cool boutique hotel on Louisville’s party-centric Whiskey Row. Plus, this place is pet-friendly if you’re planning on traveling with your furry friend. Your pups will even be spoiled with free treats and amenities in the room and will be pampered by the wait staff in the hotel’s pet-friendly restaurants!
One of the coolest things about Aloft is that all apartment-style rooms are designed to feel like a home away from home. You’ll love the mid-century decor, plush platform beds, and ergonomic workstations. The mini-fridges, coffeemakers, and complimentary wifi are much-appreciated extra features.
You can pick up snacks and drinks from the hotel’s 24-hour grab-and-go market, Re:fuel. Or, if you want to get a taste of Louisville’s Urban Bourbon Trail, head down to the hotel’s bar and restaurant, Corner. Take a seat on the patio – which overlooks Whiskey Row – and order up a snifter of one of the bar’s 80 Kentucky bourbons.
Hyatt Regency Louisville is one of the best hotels in Louisville if you want to be right in the heart of town. Not only is the hotel connected to the Kentucky International Convention Center via a skywalk but Waterfront Park, the Muhammad Ali Center, and the Louisville Slugger Museum and Factory are all a short stroll away.
When you’re not exploring all of Louisville’s top attractions, you can swim laps in the indoor pool, play a round of tennis at the on-site tennis court, or work up a sweat in the fully outfitted fitness center. In the mornings, head down to the on-site Starbucks for your favorite coffee drink. And for farm-to-table meals, Sway serves up Southern-inspired dishes like chicken fritter sandwiches, spicy shrimp and grits, and fried green tomatoes.
At the end of an action-packed day, you’ll love unwinding in the contemporary rooms. You can get comfy on the signature Hyatt Grand Bed, have a movie night with the 65-inch HDTV, and catch up on work at the spacious workstation. If you’re in town for a special occasion, the VIP suite is well worth splurging on for its fully equipped kitchenette, lavish living room, and sweeping city views.
Set right in the heart of town, the Omni is surrounded by all of Louisville’s best attractions. But with so many amazing amenities, you won’t have to leave this gem of a hotel if you don’t want to!
One of the coolest things about the Omni is the rooftop patio. Head up here and you can float the day away in the rooftop pool, sip cocktails with a view at the pool bar, warm up around the fire pits, or get pampered at the spa and salon. Wander around the hotel and you’ll also find a full bowling alley and a hidden speakeasy-style lounge.
When it comes to on-site drinking and dining, you’ll have plenty to choose from. From a premium steakhouse to a bourbon tasting room to an excellent room service menu, the Omni has something to suit all tastes.
The newly designed, Louisville-themed rooms are outfitted with unique features, including bourbon splash carpet, Louisville Slugger-inspired lamps, and a curated bourbon bar. If you want to stay in the best room in the house, the Luxury King Corner Suite boasts wraparound floor-to-ceiling windows, a luxurious living room and wet bar, and a spa-like bath with a standalone soaking tub.
Louisville is home to not one but two Aloft hotels! So if you want to be based in the east of the city – away from the hustle and bustle of downtown – Aloft Louisville East is an excellent option.
Whether you’re in town on business or for a much-needed vacation, Aloft East has everything you need for a comfortable stay. You can work up a sweat in the 24-hour fitness center, go for a swim in the indoor pool, or get some work done in the business center.
If you’re craving a morning cup of coffee or a late-night snack, the hotel has a convenient 24-hour store. Before heading out for the night, you can socialize over cocktails and light bites at the popular W XYZ Bar. Plus, you’ll be surrounded by plenty of restaurants if you want to dine out.
After a long day, you’ll love resting up in the stylish rooms. All rooms boast comfy signature pillow top beds, plug-and-play connectivity stations, luxurious baths with custom Bliss Spa amenities, and floor-to-ceiling windows with city views.
Hilton Garden Inn Louisville is another excellent option if you want to stay in eastern Louisville. Downtown Louisville is a quick 15-minute drive away. Plus, Mall St. Matthews is right across the street, so you’ll have easy access to all sorts of shops and restaurants.
Rooms are outfitted with platform beds with luxury Serta mattresses, colorful artwork, and 42-inch flat-screens. The microwaves, mini-fridges, and Keurig coffeemakers are all handy added features. If you’re craving a late-night snack or drink, there’s also a 24-hour convenience store on-site.
When you’re not out on the town, you can splash around in the heated indoor pool or keep up with your workout routine in the 24-hour fitness center. Once you work up an appetite, head downstairs to the hotel’s Garden Grille & Bar for cooked-to-order breakfasts, a seasonal selection of flatbreads, and Hilton Garden’s signature Mobley burgers. The restaurant also has a popular bar if you’re in the mood for a cocktail or craft brew.
If you want to be based directly on the Urban Bourbon Trail, Louisville Marriott Downtown is one of the best hotels in Louisville. From distilleries to cocktail bars, this is the place to be if you’re in town to let loose for the weekend! Plus, the 4th Street Live! Entertainment District is just outside your door.
Standard rooms boast plush beds, 55-inch flat-screen TVs, and deluxe ensuites with Bath and Body Works toiletries. It’s well worth upgrading to one of the Club Level rooms for exclusive access to M Club, as well as the lounge’s complimentary breakfasts, snacks, and beverages.
The hotel also has a large indoor pool, a 24-hour fitness center, and a yoga studio. Head down to the stylish lobby and you’ll find an on-site Starbucks, a chic lobby bar, and a private Bourbon Tasting Room.
Porch Kitchen & Bar is the perfect place to mingle with family and friends over drinks and Southern food. The menu boasts indulgent dishes like lump crab hushpuppies, Southern fried chicken, and baked mac and cheese. The bar also has plenty of large TVs in case you want to watch the big game!
That completes our list of the 12 best Louisville hotels! Did we miss any cool boutique hotels in Louisville? Comment below so we can add them to the list!
Didn’t find the perfect Louisville hotel? try searching here:Booking.com
Planning a trip to Kentucky? Check out our favorite books and travel guides!