The Best Boutique Hotels in St. Louis, Missouri

12 Cool Boutique Hotels in St. Louis, Missouri

When most people think of St. Louis, they immediately think of its 630-foot Gateway Arch. The landmark pays tribute to the city’s historic role as the “Gateway to the West” during the westward expansion in the 19th century. St. Louis might be famous for its grand arch, but as the largest city in Missouri, there’s much more to this place than its iconic arch!

Today, the city has flourished into a hub for food, art, culture, nightlife, and, of course, history. From world-class sports venues to historical sites to buzzing nightlife venues, it’s impossible to get bored in this dynamic city.

No trip to St. Louis is complete without checking out all the attractions Forest Park has to offer. Families will love exploring the park and stopping off at the St. Louis Zoo, the St. Louis Science Center, and the Saint Louis Art Museum. After that, head over to Busch Stadium and catch a Cardinal’s baseball game! 

From marveling at the 19th-century Old Cathedral to walking in the footsteps of explorers on the Lewis and Clark Hiking Trail to sampling the best of Missouri’s barbecue at the iconic Bogart’s Smokehouse, St. Louis has something to suit all tastes.

It’s no surprise that St. Louis boasts all sorts of incredible historic hotels, luxurious retreats, and art-filled boutique hotels. So many, in fact, that you might have a hard time choosing the perfect one. So we’ve created a list of the 12 best hotels in St. Louis to help you plan your perfect getaway!

Where to Stay in St. Louis

Where to Stay in St. Louis: Best Boutique Hotels

It’s no surprise that some of the best hotels in St. Louis are clustered around the downtown area. Whether you’re in town for work or play, you’ll have easy access to major attractions – from the America’s Center Convention Complex to Busch Stadium. Plus, you can easily walk to all sorts of trendy restaurants and stylish rooftop bars from your hotel. 

If you’d prefer to be more removed from the hustle and bustle of downtown, Forest Park is an amazing part of town. The 1,300-acre park is brimming with family-friendly attractions, scenic trails, and pop-up events, so it’s a great place for families. 

Grand Center is nestled between downtown and Forest Park and is the perfect pick if you’re looking for the best of both worlds. If you’re an art and culture buff, you’ll be a stone’s throw from the Sheldon Concert Hall and Art Galleries, Fox Theatre, and Kranzberg Art Centre. Plus, you’ll find all sorts of cool hotels in this part of town.

Located just south of downtown, Lafayette Square is ideal for those wanting to stay in a more residential part of town. This just happens to be home to the oldest publicly owned park west of the Mississippi and is chock full of charming shops and eateries, quaint tree-lined streets, and architecturally stunning buildings, homes, and hotels!

The 12 Best Boutique Hotels in St. Louis, Missouri 

1. The Last Hotel 

If you want to stay in the coolest hotel in St. Louis, look no further than The Last Hotel. The beautiful Neoclassical and Art Deco-style building first opened as the International Shoe Company in 1909. So expect the perfect blend of modern amenities and original stone carvings, intricate metalwork, and terrazzo floors.

The Last Hotel recently opened its doors in 2019 so expect everything to be new and top of the line! The stylish rooms are all outfitted with mid-century furnishings, original barrel ceilings, and deluxe ensuites. If you want something a bit more decadent, the VIP suites boast spacious living areas, in-room bars, and custom subway-tiled walk-in showers. 

Head up to the rooftop, where you’ll find a large outdoor pool and a sundeck lined with stylish loungers. If you’re in the mood for a tipple with a view, the rooftop bar is the perfect spot to meet up with friends for sunset happy hour drinks. 

You can raid The Pantry if you’ve got a craving for a snack or drink. For something more substantial, the hotel’s Ultima Cucina serves up excellent wood-fired pizzas and handmade pastas.

2. St. Louis Union Station Hotel

This iconic 1894 building once housed the Union Railway Station so expect to find all sorts historical references throughout this unique hotel. Step inside the grand lobby of the St. Louis Union Station Hotel and you’ll immediately see what all the fuss is about. The historic space boasts dramatic 65-foot vaulted ceilings, Tiffany stained glass windows, and stunning archways. 

When you’re not out on the town, you can go for a swim at the (seasonal) outdoor swimming pool, keep up with your workout routine in the fully outfitted gym, or sip coffee at the on-site 1920s-themed Starbucks! Don’t miss out on the hourly 3D light show on the lobby’s sky-high ceilings.

Even if you’re not staying here, be sure to have at least one meal in the recently renovated Grand Hall. The Grand Hall experience features excellent food, a historic setting, and a unique high-def projection mapping experience. 

After a long day, you’ll love resting up in the comfy rooms. All rooms are outfitted with plush beds, a 42-inch HDTV, and ergonomic workstations. The mini-fridge, Cuisinart coffeemakers, and luxe bath products are thoughtful extras.

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3. Four Seasons St. Louis 

Where to Stay in St. Louis, Missouri: Four Seasons St Louis
Photos: Four Seasons

It’s no surprise that the Four Seasons is one of the most luxurious hotels in the city. Located in the heart of the entertainment district, you’ll find endless things to do in this part of town. But with so many amazing amenities, you’ll probably never want to leave this resort-style hotel! 

One of the coolest things about the Four Seasons is its Sky Terrace. Head up to the eighth story and you’ll find an outdoor pool, luxurious private cabanas, and a chic pool bar and restaurant. The hotel also boasts a lavish on-site wellness center with a spa, two steam rooms, multiple whirlpools, and a state-of-the-art gym. 

If you’re hungry, you can dine on South American-inspired fare at James Beard Award-Winning Chef Gerard Craft’s restaurant Cinder House. Or, if you’re too exhausted to go out, throw on your bathrobe and slippers and order room service. 

All rooms boast stylish furniture, floor-to-ceiling windows, and bathrooms with deep soaking tubs and rainfall showers. But we highly recommend booking one of the Premiere Arch-View Rooms for their amazing views!

4. Angad Arts Hotel 

Art enthusiasts will definitely want to stay in the Angad Arts Hotel. Set right in the heart of the Grand Center Arts District, you’ll be able to walk to all sorts of museums, art galleries, Fox Theatre, and Sheldon Concert Hall. Plus, this hotel is brimming with local art and colorful decor!

Each floor of this new hotel boasts a different color. The idea is to pick a color based on how you want to feel! You can choose yellow for curious, blue for free, and green for rejuvenated. 

No matter which color you choose, rooms boast monochromatic furniture and decor, a massive mural created by a local artist, and an ergonomic workstation. If you want to feel emboldened, book the red Loft King, which is outfitted with a red standalone soaking tub in the bedroom!

Explore the hotel and you’ll find rotating art exhibits from local artists. Be sure to head up to the rooftop patio, where you can sip cocktails while taking in views of the iconic Gateway Arch. With so many cool amenities and artsy touches, there’s a reason this is considered one of the most unique boutique hotels in St. Louis! 

5. The Moonrise Hotel

Yet another completely one-of-a-kind hotel in St. Louis, the Moonrise Hotel might just be the perfect pick if you’re looking for something totally offbeat. As the name implies, this unique hotel is entirely space-themed. You’ll be wowed by the iridescent walls, lit-up rainbow staircase, and funky space art the minute you step into the lobby!

The luxurious boutique rooms boast mid-century furniture, Serta Enrapture Euro Top beds, and ensuites with Symmons rain showers and eco-friendly Aveda products. For something totally unique, book one of the whimsical Celebrity Suites, which are themed after icons from the St. Louis Walk of Fame! This hotel is also very pet-friendly if you’re planning on traveling with your furry friend. 

For sunset drinks, head up to the 8th-floor Rooftop Garden Bar for signature cocktails, creative appetizers, and the world’s largest man-made moon! For dinners, the hotel’s award-winning Eclipse Restaurant specializes in locally sourced American cuisine. This is also a very popular brunch spot on Saturdays and Sundays.

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6. Live! by Loews – St. Louis 

If you’re in town to catch a Cardinals game, Live! by Loews is just across from Busch Stadium. But even if you’re not a sports fan, the hotel is set in the middle of the city’s entertainment hub, Ballpark Village. Not only will you be surrounded by some of the best restaurants and nightlife venues in town but the Gateway Arch is an easy 10-minute walk away. 

You’ll love crashing out in the stylish rooms, which seamlessly blend contemporary decor with design paying homage to the origins of American baseball. Spacious rooms all boast floor-to-ceiling windows with sweeping city views, cozy workstations and sitting areas, and deluxe ensuites with Beekman Brothers toiletries. If you want to go big, book the One Bedroom King Suite, which has a large private balcony overlooking Busch Stadium!

When it comes to drinking and dining, you’ll be spoiled for choice. You can pick up grab-and-go snacks and beverages at the River Market, drink beers and watch the big game at The Bullock’s chic outdoor terrace, enjoy premium surf and turf at Clark & Bourbon, or choose from 480 curated spirits at The Whiskey Room. Of, if you’re too exhausted to go out, just order room service!

7. The Cheshire

Where to Stay in St. Louis, Missouri: The Cheshire
Photos: The Cheshire

Whether you’re in town for work or for play, The Cheshire has everything you need for a comfortable and luxurious stay. Plus, the customer service here is arguably the best in town. They even promise to pamper your pups if you decide to bring them along!

This Tudor-style building was designed to mimic a traditional British inn. From decor to dining, expect to find all sorts of British touches throughout this unique boutique hotel. 

Each room is themed after a different British author and boasts classic furniture and decor, a writing desk with a leather chair, and a cozy sitting area. You’ll love the extras, including the Keurig coffeemaker, the Acca Kappa bath products, and the biography and various works of your designated British author.

When it comes to food and drink, you’ll have plenty to choose from. You can sip beer and snack on pub grub at the Fox & Hounds British-style tavern, enjoy pizza and pasta at Basso Gastropub, and dine on American fare at Boundary Restaurant. If you need a pick-me-up in the morning, there’s also an on-site Starbucks.

8. The Ritz-Carlton, St. Louis 

The Ritz-Carlton is located a 15-minute drive from the heart of town in the trendy Arts and Garden District of Clayton. But with so many cool and luxurious amenities, it won’t be a surprise if you choose to just hang out around this dreamy hotel. If you’re searching for a luxurious stay, this is easily one of the best hotels in St. Louis!

You can spend your days wining and dining at St. Louis’s largest dine-in wine cellar, picking out premium cigars in the private cigar club, getting massages at the spa, or keeping up with your workout routine in the state-of-the-art fitness center. 

Even the standard rooms at the Ritz are the epitome of luxury. You’ll love the French doors that open to the private Juliet balcony, the plush bed and regal chaise lounge, and the Carrara marble bath with Asprey luxury toiletries. 

If you’re in town for a special occasion, the lavish Club Level Executive Suite is worth the upgrade. The suite gives you exclusive access to the Club Lounge, personalized concierge service, and in-room amenities like massive marble baths with separate showers and soaking tubs!

If you’re hungry, you can dine on the excellent Mediterranean fare at Casa Don Alfonso. Or for something lighter, head down to the Lobby Lounge for craft cocktails and small plates. The elegant bar also has live music and sushi on select evenings.

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9. Magnolia Hotel St. Louis

Magnolia Hotel is the perfect pick if you’re looking for a luxurious boutique hotel located right in the heart of town. You’ll be able to walk to the city’s major attractions, including America’s Center, Busch Stadium, and the Gateway Arch. Plus, this beautiful 1924 building is listed on the National Register of Historic Places, so you know it’s something special! 

With large windows, all rooms are filled with light and boast a soothing color palette and mid-century furniture. You’ll love the comfy beds and oversized headboards, ergonomic workstations, and large flat-screens. If you want to splurge, the Corner Suites are well worth it for their stylish living rooms and French doors that offer sweeping views of the Gateway Arch. 

The hotel also has an on-site gym so you can keep up with your workout routine during your stay. If you want to dine at the hotel, Robbie’s Restaurant dishes out locally sourced American cuisine and artisanal cocktails. Before you head back to your room in the evening, be sure to take advantage of the complimentary milk and cookies!

10. The Chase Park Plaza

Best St. Louis Hotels: The Chase Park Plaza
Photos: The Chase

Tucked away in the Central West End, The Chase is one of the most luxurious historic hotels in St. Louis. The 1922 Art Deco-style high-rise is just across from Forest Park. The park is home to all sorts of scenic trails, as well as the Saint Louis Zoo, the St. Louis Art Museum, and the St. Louis Science Center. 

While you’ll have easy access to some of the city’s best attractions, the hotel prides itself on being a “city within a city.” From a barbershop to a historic five-screen cinema, you’ll find endless things to do in this one-of-a-kind hotel! 

One of the coolest things about The Chase is the Mediterranean-style pool area, which boasts fountains, stone-carved porticoes, and an outdoor fireplace. You’ll also find an 18,000-square-foot fitness center, a 24-hour business station, and plenty of drinking and dining options at the hotel. 

You can socialize over handcrafted cocktails and creative gastropub fare at Chase Club, indulge on “Food is Art” dishes and innovative “Liquid Art” cocktails at The Preston, or simply curl up in your bathrobe and order room service. The culinary star of this hotel is The Tenderloin Room, which has been an institution in St. Louis since the 1960s!

After a long day, you’ll love unwinding in your newly renovated room, which features the perfect blend of historic charm and modern comfort and decor. All rooms are outfitted with comfy pillow top beds, large writing desks, and marble bathrooms with designer toiletries.

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11. Hyatt Regency St. Louis at The Arch

If you want to stay in a chic hotel near the Gateway Arch or Ballpark Village, the Hyatt Regency St. Louis at The Arch might just be the one! Plus, this hotel is pet-friendly if you plan on bringing your four-legged friend along!

You’ll love the contemporary rooms, which feature signature Hyatt Grand Beds, 50-inch flat-screen TVs, and deluxe baths with KenetMD bath products. The blackout blinds, coffeemakers, and mini-fridges are much-appreciated extra amenities. Upgrade to the Regency Club rooms, and you’ll get access to the exclusive club for free daily breakfasts, evening appetizers, and all-day drinks and snacks!

In the mornings, grab your favorite coffee drinks and pastries at the on-site Starbucks. The hotel’s Brewhouse Historical Sports Bar is the place to watch a Cardinal’s game with a local craft brew or two. If that’s not enough, the hotel boasts its very own Ruth’s Chris Steak House if you’re craving a juicy steak and a fine glass of wine!

12. Hotel Indigo

St. Louis Boutique Hotels: Hotel Indigo
Photos: Hotel Indigo

Hotel Indigo is an excellent option if you want to stay in one of the coolest boutique hotels in St. Louis. Whether you’re in town for work or play, you’ll find everything you need to feel right at home at Hotel Indigo. You can even bring your dog along on your trip since this is a pet-friendly hotel!

The hotel is set right in the heart of downtown St. Louis, so prime attractions like the Gateway Arch and the mighty Mississippi River are just steps away. Plus, there’s a MetroLink light rail stop nearby – so exploring the city is a breeze!

The sleek black and white rooms boast plush beds with crisp white linens, handy workstations, large flat screens, and mid-century modern furniture and decor. Depending on which eclectic room you choose, you’ll get cool features from funky St. Louis-themed wall murals to wraparound windows with epic city views.

Explore this chic hotel and you’ll find the popular Switchlist restaurant, which serves up innovative sharable plates. Head up to the rooftop Penthouse Bar where you can sip sunset craft cocktails with friends and family. It’s the perfect way to end an action-packed day in St. Louis!

That completes our list of the 12 best St. Louis hotels! Did we miss any cool boutique hotels in St. Louis? Comment below so we can add them to the list!

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Crisalyn Scheel
Crisalyn Scheel
22 days ago

What about Hotel Saint Louis? #7 in the Marriott Autograph Collection “Celebration of Saint Louis” . 5 star 2 diamond awards. Central downtown. The history of the building alone is worth knowing

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